Find our latest articles on our research here.

  • Postural Orthostatic Tachycardia Syndrome (POTS)
    Postural Orthostatic Tachycardia Syndrome (POTS) Discussion document: Dr Graham Exelby: Summary: Postural orthostatic tachycardia syndrome (POTS) is defined as orthostatic intolerance associated with tachycardia exceeding 120 beats per minute or an increase in the heart rate of 30 beats per minute from baseline within 10 minutes of changing the posture from a lying toContinue reading “Postural Orthostatic Tachycardia Syndrome (POTS)”
  • Dysautonomia and sleep apnoea
    Obstructive sleep apnoea produces major acute haemodynamic changes and causal relationships with arterial hypertension and cardiovascular morbidity have been proposed.(1) Autonomic dysfunction has been independently associated with obstructive sleep apnoea (OSA), and while autonomic abnormalities are generally considered to be secondary to OSA, it is also felt that autonomic dysfunction may also contribute to OSA.Continue reading “Dysautonomia and sleep apnoea”
  • Preventing Vascular Ageing
    Arteriosclerosis is an Inflammatory Process The last decade has shown an increase in the relevance of inflammation and its mediators in vascular biology; thus, the role of inflammation during atherogenesis is now a matter of intense investigation. Basic science studies proved that elements belonging to both innate and adaptive immunity can be involved in theContinue reading “Preventing Vascular Ageing”
  • Autonomic Nervous System
    Acknowledgments: This article is based principally on: ANS Balance Assessment.  Bioscan Medeia Inc.. “The Autonomic Nervous System (ANS) is the involuntary division of the nervous system. It consists of autonomic neurons that conduct impulses from the central nervous system (brain and/or spinal cord) to glands, smooth muscle and cardiac muscle. ANS neurons are responsibleContinue reading “Autonomic Nervous System”
  • Oxidative Stress
    “We know that we must constantly consume oxygen in order to carry out normal cellular metabolism. On a cellular basis, oxygen is mostly used in organelles called mitochondria. These organelles have been called our cells’ “power-plants” because this is where raw fuels that we eat (proteins, carbohydrates, and fats) are converted into a useful formContinue reading “Oxidative Stress”
  • Popliteal Vein Compression Syndrome
    Popliteal Vein Compression Syndrome is one of a number of mechanical compression syndromes that can cause a variety of medical problems. Probably the most commonly known one is the controversial Thoracic Outlet Compression Syndrome which can affect nerves, veins and arteries, or even all of them, when the arm is raised eg to dry yourContinue reading “Popliteal Vein Compression Syndrome”
  • Lectins
    Lectins were first discovered in 1888 by Stillmark while investigating the toxic effects of the castor bean. Over the past 30 years lectins have been shown to be relevant in a wide variety of medical problems that are endemic in our Western society including rheumatoid and other auto-immune arthritis, obesity, auto-immune disease, arteriosclerosis and allergy.Continue reading “Lectins”
  • Irritable Bowel Syndrome
    A traditional view of IBS From “Irritable Bowel Syndrome (IBS), BetterHealth Channel from Victorian Government. “Around one in five Australians experiences the unpleasant symptoms of irritable bowel syndrome (IBS) at some time. These include abdominal pain, mucus in the stools, and alternating diarrhoea and constipation. Other terms for irritable bowel syndrome include ‘spastic colon’ andContinue reading “Irritable Bowel Syndrome”
  • Intra-abdominal Vascular Compression Syndromes
    Looking closely at causes for autonomic dysfunction, there are quite a number of areas where compression of the arteries, veins and the accompanying autonomic nerves can occur. The most common appear to be in the legs, at the origin of the Adductor Canal, some 12 cm above the femoral condyle of the knee, and theContinue reading “Intra-abdominal Vascular Compression Syndromes”
  • Joining the dots in POTS, Migraine and Fibromyalgia
    One of the safest aspects about modern medicine is its conservatism, and the need to work within accepted and proven guidelines. It is a safeguard against enthusiastic or entrepreneurial management, and usually protects against unsafe and dangerous practices. This discussion document does not follow mainstream evidence-based medicine and as such, it must be read andContinue reading “Joining the dots in POTS, Migraine and Fibromyalgia”
  • My Journey
    My Journey Around 20 years ago, I was fortunate to meet, and later work with, one of the great pioneers in food related disease, the allergist Dr Mervyn Garrett. For decades, he has been able to prove the relationship between types of food to diseases such as eczema, irritable bowel, colic, reflux, and many more.Continue reading “My Journey”
  • Inflammation and Autonomic Dysfunction
    The rest of this information is generic and my interpretation of current knowledge. This is not mainstream medicine and as such, it must be read and seen as research-based rather than evidence-based which is how medicine usually works, and which does provide a safety net against extreme concepts. Working through the problems leading to POTSContinue reading “Inflammation and Autonomic Dysfunction”
  • Aortic root and arch dilation
    Aortic root and arch dilatation. Preliminary studies suggest a link between aortic root and arch dilatation with thoracic outlet vein compression, the MTHFR mutation, as well as hypermobility syndromes. At present we are investigating the hypothesis that catecholamine and/or inflammatory responses and baroreceptor signaling from vascular compression syndromes, particularly thoracic outlet syndrome are responsible forContinue reading “Aortic root and arch dilation”
  • Migraine
    Migraine remains a poorly understood disease, and with this the management traditionally is frequently unsatisfactory.   Migraine headaches are characterized by a throbbing or pounding pain, and are classically located on one side of the head, although they can occur all over. 
  • Fibromyalgia Syndrome
    Fibromyalgia syndrome (FMS) is a common yet generally poorly understood syndrome characterized by diffuse chronic pain accompanied by other symptoms such as fatigue, poor sleep and stiffness, often in the absence of any obvious disease or pathology.

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